GRA1 protein vaccine confers better immune response compared to codon-optimized GRA1 DNA vaccine

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GRA1 protein vaccine confers better immune response compared to codon-optimized GRA1 DNA vaccine.

The present study evaluates immunogenicity and protection potency of a codon-optimized GRA1 DNA vaccine, wild type GRA1 DNA vaccine and an adjuvanted recombinant GRA1 protein vaccine candidate in BALB/c mice against lethal toxoplasmosis. Of the three GRA1 vaccines tested, the recombinant GRA1 protein vaccine results reveal significant increase in immune response and prolonged survival against a...

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Antitumor Response to a Codon-Optimized HPV-16 E7/HSP70 Fusion Antigen DNA Vaccine.

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ژورنال

عنوان ژورنال: Vaccine

سال: 2007

ISSN: 0264-410X

DOI: 10.1016/j.vaccine.2006.10.060